Cystic fibrosis is inherited in which pattern?

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Multiple Choice

Cystic fibrosis is inherited in which pattern?

Cystic fibrosis is inherited in an autosomal recessive pattern. This means two mutated copies of the CFTR gene, located on an autosome, are needed for the disease to manifest. Carriers have one mutated copy and typically show no symptoms. When both parents are carriers, each pregnancy has about a 25% chance of an affected child, a 50% chance of an affected carrier, and a 25% chance of an unaffected non-carrier. This pattern affects both sexes equally and can skip generations, unlike autosomal dominant (which requires only one mutated copy), X-linked dominant (transmission favors males in some patterns), or mitochondrial inheritance (passed from mother to all children).

Cystic fibrosis is inherited in an autosomal recessive pattern. This means two mutated copies of the CFTR gene, located on an autosome, are needed for the disease to manifest. Carriers have one mutated copy and typically show no symptoms. When both parents are carriers, each pregnancy has about a 25% chance of an affected child, a 50% chance of an affected carrier, and a 25% chance of an unaffected non-carrier. This pattern affects both sexes equally and can skip generations, unlike autosomal dominant (which requires only one mutated copy), X-linked dominant (transmission favors males in some patterns), or mitochondrial inheritance (passed from mother to all children).

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