Browse all practice questions for the PANCE Pulmonology Practice Test. Search by topic, open any question and review its full explanation, then test yourself in the practice quiz.

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  • In persistent asthma, what is the first-line long-term controller, and what class is added for moderate to severe disease?
  • Which biologic targets IL-5 signaling in severe eosinophilic asthma?
  • What exposure history is typical for hypersensitivity pneumonitis and what are its classic HRCT findings?
  • Silicosis is classically linked to which exposure?
  • Which regimen for latent TB is given weekly?
  • What range is considered normal for FVC as a percent of predicted value?
  • What are the Berlin criteria for diagnosing ARDS?
  • What is a common first-line therapy for obstructive sleep apnea?
  • Which of the following best describes the exact criteria for pre-capillary pulmonary hypertension on hemodynamics?
  • Which ABG pattern is characteristic of respiratory acidosis?
  • Which of the following is NOT a risk factor for asthma exacerbations?
  • What is the role of nucleic acid amplification testing (NAAT) in TB testing?
  • Which finding is characteristic of a tension pneumothorax?
  • What is the typical pattern of low-dose CT screening interval for at-risk individuals?
  • In restrictive lung disease, the FEV1/FVC ratio is typically:
  • Which antiviral agent is used for influenza treatment?
  • Which management principle is essential in asthma care?
  • Which of the following is a common early sign of cystic fibrosis in newborns?
  • In anaphylaxis, most fatalities occur within what time frame after exposure?
  • Which condition is typically associated with a normal DLCO?
  • How should a pneumothorax be managed when it is small and stable versus large or symptomatic?
  • Which statement about community-acquired pneumonia (CAP) is true?
  • Which set of vaccines is recommended for COPD patients according to the material?
  • Which of the following is a common short-course latent TB regimen?
  • What ventilator strategy reduces mortality in ARDS?
  • Which exposure is listed as a risk factor for asthma exacerbations?
  • In active TB treatment, what describes the intensive phase?
  • What are the two main NSCLC histologies and which is more strongly associated with smoking?
  • Which condition is typically associated with reduced DLCO?
  • Deep vein thrombosis usually occurs in which region?
  • Which symptom is most commonly associated with acute pulmonary embolism?
  • Non-spirometry based asthma diagnosis relies on a peak flow increase after four weeks of inhaled corticosteroids. By how much must peak flow improve?
  • What is the recommended approach to antibiotic use in acute bronchitis when bacterial infection is not strongly suspected?
  • What does MART therapy stand for in asthma management?
  • What is the typical management for a large primary spontaneous pneumothorax in a stable patient?
  • What occupational lung disease is associated with pleural plaques and increased risk of mesothelioma and bronchogenic carcinoma?
  • Which of the following best describes the typical annual low-dose CT lung cancer screening eligibility criteria?
  • Which pathogen is associated with viral CAP?
  • What is the standard initial four-drug regimen for drug-susceptible pulmonary TB and its typical duration?
  • V/Q scan is used as an alternative to CT in PE for patients in which situation?
  • In cystic fibrosis, what is the typical chronic infection and resulting lung damage?
  • Which element is considered part of cystic fibrosis-specific multidisciplinary care?
  • What best defines chronic obstructive pulmonary disease (COPD)?
  • Which of the following is a common indication for bronchoscopy in pulmonology?
  • In ARDS, plateau pressure should be limited to what value to minimize barotrauma during low tidal volume ventilation?
  • Which of the following features best distinguishes asthma from COPD in a patient with dyspnea?
  • Which systemic symptom is listed as B signs in bronchogenic carcinoma?
  • Metabolic acidosis is caused by which of the following?
  • Which statement defines Forced Vital Capacity (FVC) in spirometry?
  • Lung‑oxygen therapy (LTOT) is indicated for COPD when PaO2 meets which criterion?
  • According to USPSTF, annual low-dose CT screening is recommended for which population?
  • Which adventitious lung sound is high-pitched and musical?
  • Which of the following is considered a red flag sign in asthma?
  • In sarcoidosis, which radiographic finding is NOT typical?
  • Which asthma category best describes daytime symptoms more than 2 days per week and nighttime symptoms more than 2 nights per month?
  • Which measures are recommended for CAP prevention?
  • Which adventitious sound is snoring or gurgling and results from fluid or obstructions in large airways?
  • Which of the following is not a prevention strategy for influenza?
  • Which of the following is NOT an indication for pulmonary function testing (PFT)?
  • Pre-bronchodilator spirometry findings that support an asthma diagnosis include which of the following?
  • Asthma classification includes which categories?
  • In tension pneumothorax, which radiographic or physiologic change is typical?
  • Compared with intermittent asthma, persistent asthma is characterized by which of the following?
  • In suspected acute bronchitis, which finding is most consistent?
  • Which of the following best characterizes obstructive sleep apnea?
  • What is considered a normal FEV1 as a percent of predicted value?
  • In the treatment of drug-susceptible TB, which four drugs constitute the initial regimen?
  • For CAP in patients over 65 or with comorbidities, which regimen is appropriate?
  • Small cell lung cancer is typically characterized by which of the following?
  • On chest radiograph, a negative result most strongly suggests latent TB infection rather than active disease.
  • In carcinoid tumors of the lung, which feature is commonly observed?
  • Which organism is a typical pathogen in community-acquired pneumonia (CAP)?
  • If non-invasive ventilation fails in COPD with acute hypercapnic respiratory failure, what is the recommended next step?
  • Which is a typical physical finding in a patient with pleural effusion?
  • What does a reduced DLCO suggest in a patient with dyspnea and a normal chest radiograph?
  • How is anaphylaxis diagnosed?
  • In hospital-acquired pneumonia with risk for MRSA and Pseudomonas, which empiric therapy is most appropriate?
  • Which of the following is a first-line empiric therapy for outpatient CAP in a healthy adult without risk factors for drug resistance?
  • Which organism is most commonly associated with chronic infection in the lungs of individuals with cystic fibrosis?
  • In hypoxemic respiratory failure, which of the following is an appropriate management step beyond treating the underlying cause?
  • Which clinical rule estimates pretest probability for pulmonary embolism and guides imaging?
  • Which term describes rough, grating sounds produced by inflamed pleural surfaces rubbing together?
  • Cardiopulmonary exercise testing (CPET) combines the routine measurements taken during incremental exercise with which of the following analyses?
  • DLCO testing evaluates diffusion capacity for which gas?
  • In children aged 0-4 years with asthma, initial therapy commonly includes which regimen?
  • What is first-line empiric therapy for outpatient CAP in a previously healthy adult without risk factors for drug resistance?
  • PFTs are used to assess prognosis in which scenario?
  • Which is a risk factor for asthma exacerbations?
  • Which finding indicates increased work of breathing during pulmonary inspection?
  • Which statement about latent TB treatment regimens is correct?
  • For children aged 5-11, which maintenance and reliever strategy is commonly used?
  • Which test is most commonly used to diagnose deep vein thrombosis?
  • Which HRCT pattern is most characteristic of idiopathic pulmonary fibrosis?
  • Flat or dull percussion is most consistent with which finding?
  • Which scenario describes a primary spontaneous pneumothorax?
  • What is the recommended intramuscular dose of epinephrine for a mild to moderate anaphylactic reaction?
  • How is active TB confirmed microbiologically?
  • A pulmonary nodule with doubling time between 1 month and 1 year is most concerning for which outcome?
  • On percussion, which finding indicates a healthy lung?
  • In patients co-infected with HIV and latent TB, what is a key management consideration?
  • In a severe COPD exacerbation requiring hospitalization, which of the following best describes the initial management including oxygen target and key therapies?
  • Arterial blood gas (ABG) analysis can reflect respiratory acidosis. Which statement describes a process that causes respiratory acidosis?
  • Which finding best describes acute respiratory distress syndrome (ARDS)?
  • For larger pulmonary nodules (>1 cm) in older smokers, which diagnostic step is commonly performed?
  • In COPD pharmacotherapy, what defines Group B treatment?
  • What is the primary treatment for Stage I and II non-small cell lung cancer?
  • What is the first step in the management of an anaphylactic reaction?
  • What are the core components and expected benefits of a pulmonary rehabilitation program?
  • Progression from mild to moderate to severe asthma is correlated with an increase in which of the following?
  • Which description matches vesicular breath sounds?
  • The FEV1/FVC ratio is typically expressed as a percentage. What is the normal range for this ratio?
  • For patients older than 12 with asthma and ongoing symptoms, which regimen best describes a MART-like approach?
  • Which statement best describes latent TB infection?
  • Which of the following conditions is commonly associated with obstructive lung disease?
  • Which class of antibiotics is effective against typical and atypical pathogens in CAP, particularly for healthy outpatients?
  • Elevated fractional exhaled nitric oxide (FENO) indicates which condition?
  • What distinguishes community-acquired pneumonia (CAP) from hospital-acquired pneumonia (HAP) in onset and common pathogens?
  • Which statement about COPD diagnosis and assessment is most accurate?
  • Asthma is best described as
  • In arterial blood gas interpretation, which finding indicates a primary respiratory disturbance?
  • For patients under 65 with CAP and no comorbidities, which is a reasonable first-line outpatient therapy?
  • Which spirometric change is associated with progression to moderate/severe persistent asthma?
  • What epinephrine dosing is recommended if intravenous administration is used in anaphylaxis?
  • What radiographic finding is characteristic of sarcoidosis in the lungs?
  • Which ECG finding is associated with pulmonary embolism?
  • Which statement correctly lists the categories of COPD?
  • Which auscultation and imaging finding is most characteristic of interstitial lung disease?
  • Which chest X-ray finding may be seen with pulmonary embolism?
  • What vaccines are routinely recommended for adults with chronic lung disease?
  • Arterial blood gas analysis helps differentiate which categories of disorders?
  • Which testing may be indicated as part of asthma evaluation under allergy testing, FeNO, labs, and imaging?
  • Which statement best describes large cell carcinoma of the lung?
  • Which test measures the distance a person can walk in six minutes?
  • Which ECG finding is most consistent with cor pulmonale?
  • Which testing method is commonly used to diagnose influenza during an outbreak?
  • In pediatric asthma, which clinical features indicate the need for stepping up therapy?
  • Which of the following is a cause of metabolic alkalosis?
  • For hypoxemic respiratory failure, which initial management step is commonly employed?
  • Breath sounds shift from vesicular to bronchial when there is fluid in the lung parenchyma such as pneumonia. Which condition best explains this shift?
  • Which of the following is an exacerbating condition for asthma?
  • Which statement about Homan's sign for DVT is most accurate?
  • Which statement defines pulmonary hypertension?
  • If a pneumothorax persists after chest tube drainage due to a persistent air leak, which procedure may be required?
  • For nodules smaller than 1 cm in younger nonsmokers, what is the recommended initial approach?
  • In COPD with acute hypercapnic respiratory failure, what is the preferred initial ventilatory support if not immediately intubated?
  • Which statement about TB IGRA interpretation is true?
  • What does Forced Expiratory Volume in 1 second (FEV1) measure?
  • Which characteristics of a solitary pulmonary nodule are most suggestive of malignancy?
  • Chronic hypoxemia has what effect on erythropoiesis?
  • What is the target oxygen saturation range for long-term home oxygen therapy in COPD?
  • What is the primary initial treatment for acute pulmonary embolism?
  • Which pattern is most characteristic of blue bloater (chronic bronchitis)?
  • Which lung function test uses a sealed box to measure lung volumes?
  • Which of the following is NOT a component of Virchow's triad?
  • In tension pneumothorax with clinical instability, what is the initial management step?
  • How is an obstructive pattern defined on spirometry and what value confirms obstruction?
  • What is the recommended target oxygen saturation (SpO2) for COPD exacerbations requiring hospitalization?
  • Which screening tools are commonly used to screen for obstructive sleep apnea?
  • Which category of pulmonary hypertension is caused by left heart disease?
  • Which statement best describes sarcoidosis?
  • Which imaging modality is commonly used to further evaluate a pulmonary nodule after CT?
  • Hospital-acquired pneumonia (HAP) is defined as pneumonia that develops after how many hours in the hospital?
  • In acute bronchitis with no strong suspicion of bacterial infection, what is the recommended management?
  • In spirometry, what FEV1/FVC ratio indicates obstruction, and how is severity categorized by FEV1 % predicted?
  • Which symptom set is commonly seen in CAP?
  • Alpha-1 antitrypsin augmentation is indicated for COPD due to which underlying cause?
  • What echocardiographic findings are commonly seen in Group 1 pulmonary arterial hypertension?
  • Which presentation is typical of an anaphylactic reaction?
  • Which diagnostic modality is commonly used for tissue sampling in bronchogenic carcinoma?
  • Which of the following is a sign commonly seen in asthma?
  • In hypoxemic respiratory failure, which ABG value defines hypoxemia on room air?
  • Which statement best describes typical and atypical pathogens in adult CAP and how empiric therapy is chosen?
  • Which imaging finding is classically linked to asbestos exposure?
  • Restrictive lung disease such as idiopathic pulmonary fibrosis typically shows which spirometry pattern?
  • In asthma diagnosis, what post-bronchodilator response supports the diagnosis?
  • Which statement about extrathoracic metastasis from bronchogenic carcinoma is correct?
  • In COPD exacerbation management, when should antibiotics be considered?
  • In an acute asthma exacerbation, which description best characterizes the early phase?
  • Which radiographic feature is typical of COPD on chest imaging?
  • During active TB treatment, how often should sputum AFB smear and culture be obtained until two consecutive cultures are negative?
  • Which statement best describes management of exudative pleural effusions?
  • What BAL finding is commonly associated with hypersensitivity pneumonitis?
  • Which physical findings are more likely in the later stages of COPD?
  • What is the recommended initial management for a small, stable pneumothorax?
  • What is considered the gold standard diagnostic test for pulmonary embolism, though rarely performed?
  • What does spirometry measure?
  • Which finding is most indicative of asthma when evaluating airway reversibility?
  • Which statement about COPD etiologies is accurate based on the material?
  • Which organism is considered an atypical CAP pathogen?
  • What chest X-ray findings are commonly seen with pulmonary edema?
  • In COPD exacerbation, noninvasive ventilation (NIV) is indicated when?
  • Which organism is commonly associated with typical CAP?
  • What are the AHI thresholds for mild, moderate, and severe obstructive sleep apnea?
  • Which procedure is used to obtain pleural fluid for analysis?
  • If beta-lactam allergy is present in CAP, which is an appropriate alternative?
  • Which description best defines Group 1 pulmonary arterial hypertension on hemodynamics and echocardiography?
  • If spirometry shows FEV1 at 65% predicted and FEV1/FVC 0.68, how is the obstructive defect categorized?
  • Which presentation is classic for intrathoracic metastasis from bronchogenic carcinoma?
  • Which statement correctly describes Light's criteria for pleural effusions?
  • What is a common regimen to reduce reactivation risk in latent TB infection?
  • Which of the following is an exacerbating condition for asthma?
  • Which combination makes up the intensive phase of active TB treatment?
  • Which laboratory finding is commonly associated with sarcoidosis?
  • Which laboratory finding supports a diagnosis of obesity hypoventilation syndrome?
  • Which statement best describes acute viral bronchitis?
  • Cystic fibrosis is inherited in which pattern?
  • Which statement best describes the radiographic differences between latent TB infection and active pulmonary TB?
  • If PPD or IGRA is positive, what are the next steps?
  • On CT, pulmonary emboli appear as what?
  • Which statement about PPD interpretation is correct?
  • What test confirms a diagnosis of obstructive sleep apnea?
  • D-dimer testing is most useful for which scenario in suspected DVT?
  • Which description best characterizes pink puffers (emphysema) among COPD presentations?
  • Which statement best describes the typical presentation of COPD?
  • Asbestosis is classically associated with which exposure and finding?
  • Noninvasive positive pressure ventilation (NPPV) is primarily used in COPD to address which condition?
  • Which statement best describes bronchogenic carcinoma statistics?
  • Which is the most significant risk factor for bronchogenic carcinoma?
  • Emphysema is best described as which of the following pathological changes?
  • Which of the following best describes intermittent asthma?
  • Which finding is most characteristic of an acute COPD exacerbation?
  • Tactile fremitus is typically increased with which condition?
  • What test confirms cystic fibrosis in suspected patients?
  • Which tests are typically used in the workup of CAP?
  • How do you calculate the alveolar-arterial (A-a) gradient and what does an increased gradient suggest?
  • Which feature is typical of squamous cell carcinoma of the lung?
  • Which biologic is an anti-IgE therapy used in severe allergic asthma?
  • FEV1/FVC ratio helps differentiate obstructive versus restrictive lung disease. In obstructive diseases, how does the ratio typically present?
  • Noncaseating granulomas are most characteristic of which disease?
  • In an acute asthma exacerbation, which options are commonly used as part of treatment?
  • Winter’s formula is used to determine the expected respiratory compensation in which acid-base disturbance?
  • How is TB primarily transmitted?
  • Which strategy is a key component of managing obesity-hypoventilation syndrome?
  • Respiratory alkalosis is most accurately characterized by
  • PFT screening is particularly used to evaluate which scenario?
  • Adenocarcinoma of the lung tends to be located where?
  • Fractional exhaled nitric oxide (FENO) testing measures what parameter?
  • Which description best fits the typical CF lung pathology?
  • Which drug reduces the risk of COPD exacerbations but may cause psychiatric events?
  • How do latent tuberculosis infection and active pulmonary tuberculosis differ in symptoms, radiography, and microbiology?
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